RET Proto-Oncogene—Not Such an Obvious Starting Point in Cancer Therapy

SIMPLE SUMMARY: Rearranged during transfection (RET) is a transmembrane receptor tyrosine kinase that shows targetable mutations and gene fusions in a few types of cancers. Multiple kinase inhibitors, which target RET kinase, show little efficiency in tumors with RET gene alterations. Therefore, the...

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Detalles Bibliográficos
Autores principales: Kucharczyk, Tomasz, Krawczyk, Paweł, Kowalski, Dariusz M., Płużański, Adam, Kubiatowski, Tomasz, Kalinka, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657474/
https://www.ncbi.nlm.nih.gov/pubmed/36358717
http://dx.doi.org/10.3390/cancers14215298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657474/
https://www.ncbi.nlm.nih.gov/pubmed/36358717
http://dx.doi.org/10.3390/cancers14215298

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