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Naphthoquinones Oxidize H(2)S to Polysulfides and Thiosulfate, Implications for Therapeutic Applications

1,4-Napththoquinones (NQs) are clinically relevant therapeutics that affect cell function through production of reactive oxygen species (ROS) and formation of adducts with regulatory protein thiols. Reactive sulfur species (RSS) are chemically and biologically similar to ROS and here we examine RSS...

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Detalles Bibliográficos
Autores principales: Olson, Kenneth R., Clear, Kasey J., Derry, Paul J., Gao, Yan, Ma, Zhilin, Cieplik, Nathaniel M., Fiume, Alyssa, Gaziano, Dominic J., Kasko, Stephen M., Narloch, Kathleen, Velander, Cecilia L., Nwebube, Ifeyinwa, Pallissery, Collin J., Pfaff, Ella, Villa, Brian P., Kent, Thomas A., Wu, Gang, Straub, Karl D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657496/
https://www.ncbi.nlm.nih.gov/pubmed/36362080
http://dx.doi.org/10.3390/ijms232113293