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Robust Generation of Ready-to-Use Cryopreserved Motor Neurons from Human Pluripotent Stem Cells for Disease Modeling

Human pluripotent stem cell (hPSC)-derived motor neurons (MNs) act as models for motor neuron diseases (MNDs), such as amyotrophic lateral sclerosis (ALS) or spinal muscular atrophy. However, the MN differentiation efficiency and viability following cryopreservation require further development for a...

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Detalles Bibliográficos
Autores principales: Ting, Hsiao-Chien, Su, Hong-Lin, Chen, Mei-Fang, Harn, Horng-Jyh, Lin, Shinn-Zong, Chiou, Tzyy-Wen, Chang, Chia-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657726/
https://www.ncbi.nlm.nih.gov/pubmed/36362259
http://dx.doi.org/10.3390/ijms232113462