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Robust Generation of Ready-to-Use Cryopreserved Motor Neurons from Human Pluripotent Stem Cells for Disease Modeling
Human pluripotent stem cell (hPSC)-derived motor neurons (MNs) act as models for motor neuron diseases (MNDs), such as amyotrophic lateral sclerosis (ALS) or spinal muscular atrophy. However, the MN differentiation efficiency and viability following cryopreservation require further development for a...
Autores principales: | Ting, Hsiao-Chien, Su, Hong-Lin, Chen, Mei-Fang, Harn, Horng-Jyh, Lin, Shinn-Zong, Chiou, Tzyy-Wen, Chang, Chia-Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657726/ https://www.ncbi.nlm.nih.gov/pubmed/36362259 http://dx.doi.org/10.3390/ijms232113462 |
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