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Mechanistic Studies and a Retrospective Cohort Study: The Interaction between PPAR Agonists and Immunomodulatory Agents in Multiple Myeloma

SIMPLE SUMMARY: Cereblon (CRBN) is a direct binding target of immunomodulatory drugs (IMiDs) that are commonly used to treat multiple myeloma (MM). Many patients with MM have comorbidities, including diabetes and/or dyslipidemia, and are treated with peroxisome proliferator-activated receptor (PPAR)...

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Detalles Bibliográficos
Autores principales: Wu, Jian, Chu, Emily, Paul, Barry, Kang, Yubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657746/
https://www.ncbi.nlm.nih.gov/pubmed/36358696
http://dx.doi.org/10.3390/cancers14215272