Recombinant Human Proteoglycan 4 (rhPRG4) Downregulates TNFα-Stimulated NFκB Activity and FAT10 Expression in Human Corneal Epithelial Cells

Dry Eye Disease (DED) is a complex pathology affecting millions of people with significant impact on quality of life. Corneal inflammation, including via the nuclear factor kappa B (NFκB) pathway, plays a key etiological role in DED. Recombinant human proteoglycan 4 (rhPRG4) has been shown to be a c...

Descripción completa

Detalles Bibliográficos
Autores principales: Menon, Nikhil G., Suhail, Yasir, Goyal, Ruchi, Du, Wenqiang, Tanguay, Adam P., Jay, Gregory D., Ghosh, Mallika, Kshitiz, Schmidt, Tannin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657836/
https://www.ncbi.nlm.nih.gov/pubmed/36361504
http://dx.doi.org/10.3390/ijms232112711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657836/
https://www.ncbi.nlm.nih.gov/pubmed/36361504
http://dx.doi.org/10.3390/ijms232112711

Ejemplares similares