Cargando…
Recombinant Human Proteoglycan 4 (rhPRG4) Downregulates TNFα-Stimulated NFκB Activity and FAT10 Expression in Human Corneal Epithelial Cells
Dry Eye Disease (DED) is a complex pathology affecting millions of people with significant impact on quality of life. Corneal inflammation, including via the nuclear factor kappa B (NFκB) pathway, plays a key etiological role in DED. Recombinant human proteoglycan 4 (rhPRG4) has been shown to be a c...
Autores principales: | Menon, Nikhil G., Suhail, Yasir, Goyal, Ruchi, Du, Wenqiang, Tanguay, Adam P., Jay, Gregory D., Ghosh, Mallika, Kshitiz, Schmidt, Tannin A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657836/ https://www.ncbi.nlm.nih.gov/pubmed/36361504 http://dx.doi.org/10.3390/ijms232112711 |
Ejemplares similares
-
Recombinant human PRG4 (rhPRG4) suppresses breast cancer cell invasion by inhibiting TGFβ-Hyaluronan-CD44 signalling pathway
por: Sarkar, Anusi, et al.
Publicado: (2019) -
Quadruped Gait and Regulation of Apoptotic Factors in Tibiofemoral Joints following Intra-Articular rhPRG4 Injection in Prg4 Null Mice
por: Yang, Daniel S., et al.
Publicado: (2022) -
The interaction of lubricin/proteoglycan 4 (PRG4) with toll-like receptors 2 and 4: an anti-inflammatory role of PRG4 in synovial fluid
por: Alquraini, Ali, et al.
Publicado: (2015) -
Proteoglycan 4 (PRG4) treatment enhances wound closure and tissue regeneration
por: Krawetz, Roman J., et al.
Publicado: (2022) -
The autocrine role of proteoglycan-4 (PRG4) in modulating osteoarthritic synoviocyte proliferation and expression of matrix degrading enzymes
por: Alquraini, Ali, et al.
Publicado: (2017)