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Homology Modeling and Molecular Dynamics-Driven Search for Natural Inhibitors That Universally Target Receptor-Binding Domain of Spike Glycoprotein in SARS-CoV-2 Variants

The rapid spread of SARS-CoV-2 required immediate actions to control the transmission of the virus and minimize its impact on humanity. An extensive mutation rate of this viral genome contributes to the virus’ ability to quickly adapt to environmental changes, impacts transmissibility and antigenici...

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Detalles Bibliográficos
Autores principales: Ovchynnykova, Olha, Kapusta, Karina, Sizochenko, Natalia, Sukhyy, Kostyantyn M., Kolodziejczyk, Wojciech, Hill, Glake A., Saloni, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657887/
https://www.ncbi.nlm.nih.gov/pubmed/36364158
http://dx.doi.org/10.3390/molecules27217336