Human Pluripotent Stem Cell-Based Models for Hirschsprung Disease: From 2-D Cell to 3-D Organoid Model

Hirschsprung disease (HSCR) is a complex congenital disorder caused by defects in the development of the enteric nervous system (ENS). It is attributed to failures of the enteric neural crest stem cells (ENCCs) to proliferate, differentiate and/or migrate, leading to the absence of enteric neurons i...

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Detalles Bibliográficos
Autores principales: Lui, Kathy Nga-Chu, NGAN, Elly Sau-Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657902/
https://www.ncbi.nlm.nih.gov/pubmed/36359824
http://dx.doi.org/10.3390/cells11213428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657902/
https://www.ncbi.nlm.nih.gov/pubmed/36359824
http://dx.doi.org/10.3390/cells11213428

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