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Aggravated renal fibrosis is positively associated with the activation of HMGB1-TLR2/4 signaling in STZ-induced diabetic mice

Diabetic kidney dysfunction is closely associated with renal fibrosis. Although the suppression of fibrosis is crucial to attenuate kidney damage, the underlying mechanisms remain poorly understood. In this study, renal injury in diabetic mice was induced by the intraperitoneal injection of streptoz...

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Detalles Bibliográficos
Autores principales: Yuan, Yan, Liu, Yuanxia, Sun, Mengyao, Ye, Huijing, Feng, Yuchen, Liu, Zhenzhen, Pan, Lingyu, Weng, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658007/
https://www.ncbi.nlm.nih.gov/pubmed/36448056
http://dx.doi.org/10.1515/biol-2022-0506