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Anti-Metastatic Effect of Pyruvate Dehydrogenase Kinase 4 Inhibition in Bladder Cancer via the ERK, SRC, and JNK Pathways

Bladder cancer is a common global cancer with a high percentage of metastases and high mortality rate. Thus, it is necessary to identify new biomarkers that can be helpful in diagnosis. Pyruvate dehydrogenase kinase 4 (PDK4) belongs to the PDK family and plays an important role in glucose utilizatio...

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Detalles Bibliográficos
Autores principales: Lee, Eun Hye, Chung, Jae-Wook, Sung, Eunji, Yoon, Bo Hyun, Jeon, Minji, Park, Song, Chun, So Young, Lee, Jun Nyung, Kim, Bum Soo, Kim, Hyun Tae, Kim, Tae Hwan, Choi, Seock Hwan, Yoo, Eun Sang, Kwon, Tae Gyun, Kang, Ho Won, Kim, Wun-Jae, Yun, Seok Joong, Lee, Sangkyu, Ha, Yun-Sok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658024/
https://www.ncbi.nlm.nih.gov/pubmed/36362028
http://dx.doi.org/10.3390/ijms232113240