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Virtual Screening and Biological Activity Evaluation of New Potent Inhibitors Targeting Hexokinase-II

Hexokinase-II (HK-II), the rate-limiting step enzyme in the glycolysis pathway, expresses high levels of cancer cells compared with normal cells. Due to its pivotal role in the different aspects of cancer physiology including cellular proliferation, metastasis, and apoptosis, HK-II provides a new th...

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Detalles Bibliográficos
Autores principales: Liu, Ruijuan, Liu, Xuewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658052/
https://www.ncbi.nlm.nih.gov/pubmed/36364382
http://dx.doi.org/10.3390/molecules27217555