In Silico and In Vitro Studies of Benzothiazole-Isothioureas Derivatives as a Multitarget Compound for Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder. Inhibiting acetylcholinesterase (AChE), amyloid beta (Aβ(1-42)) aggregation and avoiding the oxidative stress could prevent the progression of AD. Benzothiazole groups have shown neuroprotective activity whereas isothioureas group...

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Detalles Bibliográficos
Autores principales: Rosales Hernández, Martha Cecilia, Fragoso Morales, Leticia Guadalupe, Correa Basurto, José, Olvera Valdez, Marycruz, García Báez, Efrén Venancio, Román Vázquez, Dania Guadalupe, Anaya García, Ana Paola, Cruz, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658106/
https://www.ncbi.nlm.nih.gov/pubmed/36361729
http://dx.doi.org/10.3390/ijms232112945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658106/
https://www.ncbi.nlm.nih.gov/pubmed/36361729
http://dx.doi.org/10.3390/ijms232112945

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