A 5′ UTR Mutation Contributes to Down-Regulation of Bbs7 in the Berlin Fat Mouse

The Bardet–Biedl Syndrome 7 (Bbs7) gene was identified as the most likely candidate gene causing juvenile obesity in the Berlin Fat Mouse Inbred (BFMI) line. Bbs7 expression is significantly lower in the brain, adipose tissue, and liver of BFMI mice compared to lean C57BL/6NCrl (B6N) mice. A DNA seq...

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Detalles Bibliográficos
Autores principales: Mohebian, Kourosh, Hesse, Deike, Arends, Danny, Brockmann, Gudrun A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658298/
https://www.ncbi.nlm.nih.gov/pubmed/36361806
http://dx.doi.org/10.3390/ijms232113018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658298/
https://www.ncbi.nlm.nih.gov/pubmed/36361806
http://dx.doi.org/10.3390/ijms232113018

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