Evolution of an Iron-Detoxifying Protein: Eukaryotic and Rickettsia Frataxins Contain a Conserved Site Which Is Not Present in Their Bacterial Homologues

Friedreich’s ataxia is a neurodegenerative disease caused by mutations in the frataxin gene. Frataxin homologues, including bacterial CyaY proteins, can be found in most species and play a fundamental role in mitochondrial iron homeostasis, either promoting iron assembly into metaloproteins or contr...

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Detalles Bibliográficos
Autores principales: Alves, Rui, Pazos-Gil, Maria, Medina-Carbonero, Marta, Sanz-Alcázar, Arabela, Delaspre, Fabien, Tamarit, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658677/
https://www.ncbi.nlm.nih.gov/pubmed/36361939
http://dx.doi.org/10.3390/ijms232113151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658677/
https://www.ncbi.nlm.nih.gov/pubmed/36361939
http://dx.doi.org/10.3390/ijms232113151

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