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Lipoic/Capsaicin-Related Amides: Synthesis and Biological Characterization of New TRPV1 Agonists Endowed with Protective Properties against Oxidative Stress

α-Lipoic acid is a sulfur-containing nutrient endowed with pleiotropic actions and a safe biological profile selected to replace the unsaturated alkyl acid of capsaicin with the aim of obtaining lipoic amides potentially active as a TRPV1 ligand and with significant antioxidant properties. Thus, nin...

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Detalles Bibliográficos
Autores principales: Brizzi, Antonella, Maramai, Samuele, Aiello, Francesca, Baratto, Maria Camilla, Corelli, Federico, Mugnaini, Claudia, Paolino, Marco, Scorzelli, Francesco, Aldinucci, Carlo, De Petrocellis, Luciano, Signorini, Cinzia, Pessina, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658705/
https://www.ncbi.nlm.nih.gov/pubmed/36362364
http://dx.doi.org/10.3390/ijms232113580