Site-Directed Mutants of Parasporin PS2Aa1 with Enhanced Cytotoxic Activity in Colorectal Cancer Cell Lines

Parasporin 2 has cytotoxic effects against numerous colon cancer cell lines, making it a viable alternative to traditional treatments. However, its mechanism of action and receptors remain unknown. In this study, site-directed mutagenesis was used to obtain PS2Aa1 mutants with variation in domain I...

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Detalles Bibliográficos
Autores principales: Suárez-Barrera, Miguel O., Visser, Lydia, Pinzón-Reyes, Efraín H., Rondón Villarreal, Paola, Alarcón-Aldana, Juan S., Rueda-Forero, Nohora Juliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658827/
https://www.ncbi.nlm.nih.gov/pubmed/36364090
http://dx.doi.org/10.3390/molecules27217262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658827/
https://www.ncbi.nlm.nih.gov/pubmed/36364090
http://dx.doi.org/10.3390/molecules27217262

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