Cargando…
Preinitiation Complex Loading onto mRNAs with Long versus Short 5′ TLs
The first step in translation initiation consists in the recruitment of the small ribosome onto the mRNA. This preinitiation complex (PIC) loads via interactions with eIF4F that has assembled on the 5′ cap. It then scans the 5′ TL (transcript leader) to locate a start site. The molecular architectur...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658832/ https://www.ncbi.nlm.nih.gov/pubmed/36362157 http://dx.doi.org/10.3390/ijms232113369 |