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Alphafold Predictions Provide Insights into the Structural Features of the Functional Oligomers of All Members of the KCTD Family

Oligomerization endows proteins with some key properties such as extra-stabilization, long-range allosteric regulation(s), and partnerships not accessible to their monomeric counterparts. How oligomerization is achieved and preserved during evolution is a subject of remarkable scientific relevance....

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Detalles Bibliográficos
Autores principales: Esposito, Luciana, Balasco, Nicole, Vitagliano, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658877/
https://www.ncbi.nlm.nih.gov/pubmed/36362127
http://dx.doi.org/10.3390/ijms232113346