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Bispyrrolidinoindoline Epi(poly)thiodioxopiperazines (BPI-ETPs) and Simplified Mimetics: Structural Characterization, Bioactivities, and Total Synthesis †

Within the 2,5-dioxopiperazine-containing natural products generated by “head-to-tail” cyclization of peptides, those derived from tryptophan allow further structural diversification due to the rich chemical reactivity of the indole heterocycle, which can generate tetracyclic fragments of hexahydrop...

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Detalles Bibliográficos
Autores principales: Martínez, Claudio, García-Domínguez, Patricia, Álvarez, Rosana, de Lera, Angel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659040/
https://www.ncbi.nlm.nih.gov/pubmed/36364412
http://dx.doi.org/10.3390/molecules27217585