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Spatial Memory Training Counteracts Hippocampal GIRK Channel Decrease in the Transgenic APP(Sw,Ind) J9 Alzheimer’s Disease Mouse Model

G-protein-gated inwardly rectifying potassium (GIRK) channels are critical determinants of neuronal excitability. They have been proposed as potential targets to restore excitatory/inhibitory balance in acute amyloidosis models, where hyperexcitability is a hallmark. However, the role of GIRK signal...

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Detalles Bibliográficos
Autores principales: Temprano-Carazo, Sara, Contreras, Ana, Saura, Carlos A., Navarro-López, Juan D., Jiménez-Díaz, Lydia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659077/
https://www.ncbi.nlm.nih.gov/pubmed/36362230
http://dx.doi.org/10.3390/ijms232113444