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Spatial Memory Training Counteracts Hippocampal GIRK Channel Decrease in the Transgenic APP(Sw,Ind) J9 Alzheimer’s Disease Mouse Model
G-protein-gated inwardly rectifying potassium (GIRK) channels are critical determinants of neuronal excitability. They have been proposed as potential targets to restore excitatory/inhibitory balance in acute amyloidosis models, where hyperexcitability is a hallmark. However, the role of GIRK signal...
Autores principales: | Temprano-Carazo, Sara, Contreras, Ana, Saura, Carlos A., Navarro-López, Juan D., Jiménez-Díaz, Lydia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659077/ https://www.ncbi.nlm.nih.gov/pubmed/36362230 http://dx.doi.org/10.3390/ijms232113444 |
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