Cargando…

Pharmacogenetics of Drug Metabolism: The Role of Gene Polymorphism in the Regulation of Doxorubicin Safety and Efficacy

SIMPLE SUMMARY: The effectiveness and safety of the anti-cancer agent doxorubicin (anthracycline group medicine) depend on the metabolism and retention of the drug in the human organism. Polymorphism of cytochrome p450 (CYP)-encoding genes and detoxifying enzymes such as CYP3A4 and CYP2D6 were found...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bagdasaryan, Alina A., Chubarev, Vladimir N., Smolyarchuk, Elena A., Drozdov, Vladimir N., Krasnyuk, Ivan I., Liu, Junqi, Fan, Ruitai, Tse, Edmund, Shikh, Evgenia V., Sukocheva, Olga A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659104/ https://www.ncbi.nlm.nih.gov/pubmed/36358854 http://dx.doi.org/10.3390/cancers14215436

Ejemplares similares

Dual effects of radiotherapy on tumor microenvironment and its contribution towards the development of resistance to immunotherapy in gastrointestinal and thoracic cancers
por: Zhao, Deyao, et al.
Publicado: (2023)

Pharmacogenetics in Primary Headache Disorders
por: Belyaeva, Irina I., et al.
Publicado: (2022)

Pharmacogenetics and Pain Treatment with a Focus on Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and Antidepressants: A Systematic Review
por: Zobdeh, Farzin, et al.
Publicado: (2022)

Prognostic value of proadrenomedullin in patients with COVID-19 pneumonia
por: Astapovskii, Aleksandr A., et al.
Publicado: (2022)

Temozolomide Efficacy and Metabolism: The Implicit Relevance of Nanoscale Delivery Systems †
por: Petrenko, Daria, et al.
Publicado: (2022)

Chinese Clinical Trial Registry 13-year data collection and analysis: geographic distribution, financial support, research phase, duration, and disease categories
por: Fan, Ruitai, et al.
Publicado: (2023)

Health Science Community Will Miss This Bright and Uniting Star: In Memory of Professor Gjumrakch Aliev, M.D, Ph.D.
por: Chubarev, Vladimir N., et al.
Publicado: (2021)

Molecular classification of human papilloma virus-negative head and neck squamous cell carcinomas: Cell cycle-based classifier and prognostic signature
por: Gu, Hao, et al.
Publicado: (2023)

Influence of pharmacogenetics on response and toxicity in breast cancer patients treated with doxorubicin and cyclophosphamide
por: Bray, J, et al.
Publicado: (2010)

Gene Polymorphisms and Pharmacogenetics in Rheumatoid Arthritis
por: Rego-Pérez, Ignacio, et al.
Publicado: (2008)

Stereotactic Ablative Brachytherapy: Recent Advances in Optimization of Radiobiological Cancer Therapy
por: Xue, Hui, et al.
Publicado: (2021)

Pharmacogenetics of toxicity of 5-fluorouracil, doxorubicin and cyclophosphamide chemotherapy in breast cancer patients
por: Tecza, Karolina, et al.
Publicado: (2018)

Advances in the Prevention and Treatment of Obesity-Driven Effects in Breast Cancers
por: Chen, Kuo, et al.
Publicado: (2022)

Distribution of CYP2B6 516G/T pharmacogenetically important polymorphism in the Ukrainian population
por: Filiptsova, Olga, et al.
Publicado: (2018)

Estrogen, estrogen receptors, and hepatocellular carcinoma: Are we there yet?
por: Sukocheva, Olga A
Publicado: (2018)

Expansion of Sphingosine Kinase and Sphingosine-1-Phosphate Receptor Function in Normal and Cancer Cells: From Membrane Restructuring to Mediation of Estrogen Signaling and Stem Cell Programming
por: Sukocheva, Olga A.
Publicado: (2018)

Association of Polymorphisms in Pharmacogenetic Candidate Genes with Propofol Susceptibility
por: Zhong, Qi, et al.
Publicado: (2017)

Experimental Pharmacogenetics
por: Lubs, Herbert A.
Publicado: (1964)

Using Pharmacogenetics of Direct Oral Anticoagulants to Predict Changes in Their Pharmacokinetics and the Risk of Adverse Drug Reactions
por: Shnayder, Natalia A., et al.
Publicado: (2021)

Structural Rearrangements of Carbonic Anhydrase Entrapped in Sol-Gel Magnetite Determined by ATR–FTIR Spectroscopy
por: Ivanovski, Vladimir, et al.
Publicado: (2022)

Polymorphisms of pharmacogenetic candidate genes affect etomidate anesthesia susceptibility
por: Ma, Lulin, et al.
Publicado: (2022)

Population Analysis of Pharmacogenetic Polymorphisms Related to Acute Lymphoblastic Leukemia Drug Treatment
por: Chiabai, Marcela A., et al.
Publicado: (2012)

Application of pharmacogenetics in oncology
por: Miteva-Marcheva, Nelly N., et al.
Publicado: (2020)

Comparison of FDA Table of Pharmacogenetic Associations and Clinical Pharmacogenetics Implementation Consortium guidelines
por: Pritchard, Daryl, et al.
Publicado: (2022)

Pharmacogenetics of Oral Antidiabetic Drugs
por: Becker, Matthijs L., et al.
Publicado: (2013)

The Epigenetics of Migraine
por: Zobdeh, Farzin, et al.
Publicado: (2023)

Knowledge and attitude regarding pharmacogenetics among formerly pregnant women in the Netherlands and their interest in pharmacogenetic research
por: Daud, Aizati N. A., et al.
Publicado: (2017)

Pharmacogenetics: polymorphism and genotype-phenotype correlation of drug response in indian population
por: Padh, Harish
Publicado: (2014)

Pharmacogenetics of Carbamazepine and Valproate: Focus on Polymorphisms of Drug Metabolizing Enzymes and Transporters
por: Iannaccone, Teresa, et al.
Publicado: (2021)

Cost Effectiveness of Pharmacogenetic Testing for Drugs with Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines: A Systematic Review
por: Morris, Sarah A., et al.
Publicado: (2022)

Pharmacogenetics of Type 2 Diabetes—Progress and Prospects
por: Nasykhova, Yulia A., et al.
Publicado: (2020)

Pharmacogenetics in Practice: Estimating the Clinical Actionability of Pharmacogenetic Testing in Perioperative and Ambulatory Settings
por: Smith, D. Max, et al.
Publicado: (2020)

Treatment of ADHD: Drugs, psychological therapies, devices, complementary and alternative methods as well as the trends in clinical trials
por: Nazarova, Victoria A., et al.
Publicado: (2022)

Pharmacogenetics of Chronic Pain and Its Treatment
por: Světlík, Svatopluk, et al.
Publicado: (2013)

EXPERIENCE OF PHARMACOGENETIC TESTING IN THE TREATMENT OF ANTIPSYCHOTICS
por: Kaydan, M., et al.
Publicado: (2023)

DRD4 and DAT1 in ADHD: Functional neurobiology to pharmacogenetics
por: Turic, Darko, et al.
Publicado: (2010)

Cancer pharmacogenetics
por: Marsh, S, et al.
Publicado: (2004)

Pharmacogenetics of Anticoagulants
por: Rane, Anders, et al.
Publicado: (2010)

Pharmacogenetics of osteoporosis
por: Marini, Francesca, et al.
Publicado: (2010)

The pharmacogenetics of imatinib
por: Dulucq, Stéphanie, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_sh5gkaokqh5ognam7kdnci8t0e