Diversity-Oriented Synthesis of a Molecular Library of Immunomodulatory α-Galactosylceramides with Fluorous-Tag-Assisted Purification and Evaluation of Their Bioactivities in Regard to IL-2 Secretion

Structural variants of α-galactosylceramide (α-GalCer) that stimulate invariant natural killer T (iNKT) cells constitute an emerging class of immunomodulatory agents in development for numerous biological applications. Variations in lipid chain length and/or fatty acids in these glycoceramides selec...

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Detalles Bibliográficos
Autores principales: Chen, Yeng-Nan, Hung, Jung-Tung, Jan, Fan-Dan, Su, Yung-Yu, Hwu, Jih-Ru, Yu, Alice L., Adak, Avijit K., Lin, Chun-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659121/
https://www.ncbi.nlm.nih.gov/pubmed/36362187
http://dx.doi.org/10.3390/ijms232113403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659121/
https://www.ncbi.nlm.nih.gov/pubmed/36362187
http://dx.doi.org/10.3390/ijms232113403

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