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Curcumin and Its Derivatives Induce Apoptosis in Human Cancer Cells by Mobilizing and Redox Cycling Genomic Copper Ions

Turmeric spice contains curcuminoids, which are polyphenolic compounds found in the Curcuma longa plant’s rhizome. This class of molecules includes curcumin, demethoxycurcumin, and bisdemethoxycurcumin. Using prostate cancer cell lines PC3, LNCaP, DU145, and C42B, we show that curcuminoids inhibit c...

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Detalles Bibliográficos
Autores principales: Alhasawi, Mohammed Ahmed Ismail, Aatif, Mohammad, Muteeb, Ghazala, Alam, Mir Waqas, Oirdi, Mohamed El, Farhan, Mohd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659251/
https://www.ncbi.nlm.nih.gov/pubmed/36364236
http://dx.doi.org/10.3390/molecules27217410