Buffy Coat Transcriptomic Analysis Reveals Alterations in Host Cell Protein Synthesis and Cell Cycle in Severe COVID-19 Patients

Transcriptome studies have reported the dysregulation of cell cycle-related genes and the global inhibition of host mRNA translation in COVID-19 cases. However, the key genes and cellular mechanisms that are most affected by the severe outcome of this disease remain unclear. For this work, the RNA-s...

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Detalles Bibliográficos
Autores principales: Cavalcante, Liliane Tavares de Faria, da Fonseca, Guilherme Cordenonsi, Amado Leon, Luciane Almeida, Salvio, Andreza Lemos, Brustolini, Otávio José, Gerber, Alexandra Lehmkuhl, Guimarães, Ana Paula de Campos, Marques, Carla Augusta Barreto, Fernandes, Renan Amphilophio, Ramos Filho, Carlos Henrique Ferreira, Kader, Rafael Lopes, Pimentel Amaro, Marisa, da Costa Gonçalves, João Paulo, Vieira Alves-Leon, Soniza, Vasconcelos, Ana Tereza Ribeiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659271/
https://www.ncbi.nlm.nih.gov/pubmed/36362378
http://dx.doi.org/10.3390/ijms232113588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659271/
https://www.ncbi.nlm.nih.gov/pubmed/36362378
http://dx.doi.org/10.3390/ijms232113588

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