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Development of mass allelic exchange, a technique to enable sexual genetics in Escherichia coli
Despite dramatic advances in genomics, connecting genotypes to phenotypes is still challenging. Sexual genetics combined with linkage analysis is a powerful solution to this problem but generally unavailable in bacteria. We build upon a strong negative selection system to invent mass allelic exchang...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659338/ https://www.ncbi.nlm.nih.gov/pubmed/36322728 http://dx.doi.org/10.1073/pnas.2105458119 |