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Cryo–electron microscopy structure of the H3-H4 octasome: A nucleosome-like particle without histones H2A and H2B

The canonical nucleosome, which represents the major packaging unit of eukaryotic chromatin, has an octameric core composed of two histone H2A-H2B and H3-H4 dimers with ∼147 base pairs (bp) of DNA wrapped around it. Non-nucleosomal particles with alternative histone stoichiometries and DNA wrapping...

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Detalles Bibliográficos
Autores principales: Nozawa, Kayo, Takizawa, Yoshimasa, Pierrakeas, Leonidas, Sogawa-Fujiwara, Chizuru, Saikusa, Kazumi, Akashi, Satoko, Luk, Ed, Kurumizaka, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659345/
https://www.ncbi.nlm.nih.gov/pubmed/36322721
http://dx.doi.org/10.1073/pnas.2206542119