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Generation of genome-edited chicken and duck lines by adenovirus-mediated in vivo genome editing

Conventional avian genome editing is mediated by isolation, culture, and genome editing of primordial germ cells (PGCs); screening and propagating the genome-edited PGCs; and transplantation of the PGCs into recipient embryos. The PGC-mediated procedures, however, are technically difficult, and ther...

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Detalles Bibliográficos
Autores principales: Lee, Joonbum, Kim, Dong-Hwan, Karolak, Madeline C., Shin, Sangsu, Lee, Kichoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659352/
https://www.ncbi.nlm.nih.gov/pubmed/36322747
http://dx.doi.org/10.1073/pnas.2214344119