Inhibition of connexin hemichannels alleviates neuroinflammation and hyperexcitability in temporal lobe epilepsy

Temporal lobe epilepsy (TLE) is one of the most common types of epilepsy, yet approximately one-third of patients are refractory to current anticonvulsive drugs, which target neurons and synapses. Astrocytic and microglial dysfunction is commonly found in epileptic foci and has been shown to contrib...

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Detalles Bibliográficos
Autores principales: Guo, Anni, Zhang, Huiqi, Li, Huanhuan, Chiu, Arthur, García-Rodríguez, Claudia, Lagos, Carlos F., Sáez, Juan C., Lau, Chunyue Geoffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659366/
https://www.ncbi.nlm.nih.gov/pubmed/36322757
http://dx.doi.org/10.1073/pnas.2213162119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659366/
https://www.ncbi.nlm.nih.gov/pubmed/36322757
http://dx.doi.org/10.1073/pnas.2213162119

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