Cargando…

Long-term depression–inductive stimulation causes long-term potentiation in mouse Purkinje cells with a mutant thyroid hormone receptor

Thyroid hormones (THs) regulate gene expression by binding to nuclear TH receptors (TRs) in the cell. THs are indispensable for brain development. However, we have little knowledge about how congenital hypothyroidism in neurons affects functions of the central nervous system in adulthood. Here, we r...

Descripción completa

Detalles Bibliográficos
Autores principales: Ninomiya, Ayane, Amano, Izuki, Kokubo, Michifumi, Takatsuru, Yusuke, Ishii, Sumiyasu, Hirai, Hirokazu, Hosoi, Nobutake, Koibuchi, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659369/
https://www.ncbi.nlm.nih.gov/pubmed/36322758
http://dx.doi.org/10.1073/pnas.2210645119