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Long-term depression–inductive stimulation causes long-term potentiation in mouse Purkinje cells with a mutant thyroid hormone receptor
Thyroid hormones (THs) regulate gene expression by binding to nuclear TH receptors (TRs) in the cell. THs are indispensable for brain development. However, we have little knowledge about how congenital hypothyroidism in neurons affects functions of the central nervous system in adulthood. Here, we r...
Autores principales: | Ninomiya, Ayane, Amano, Izuki, Kokubo, Michifumi, Takatsuru, Yusuke, Ishii, Sumiyasu, Hirai, Hirokazu, Hosoi, Nobutake, Koibuchi, Noriyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659369/ https://www.ncbi.nlm.nih.gov/pubmed/36322758 http://dx.doi.org/10.1073/pnas.2210645119 |
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