IGF2BP2 promotes cancer progression by degrading the RNA transcript encoding a v-ATPase subunit

IGF2BP2 binds to a number of RNA transcripts and has been suggested to function as a tumor promoter, although little is known regarding the mechanisms that regulate its roles in RNA metabolism. Here we demonstrate that IGF2BP2 binds to the 3′ untranslated region of the transcript encoding ATP6V1A, a...

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Detalles Bibliográficos
Autores principales: Latifkar, Arash, Wang, Fangyu, Mullmann, James J., Panizza, Elena, Fernandez, Irma R., Ling, Lu, Miller, Andrew D., Fischbach, Claudia, Weiss, Robert S., Lin, Hening, Cerione, Richard A., Antonyak, Marc A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659396/
https://www.ncbi.nlm.nih.gov/pubmed/36322753
http://dx.doi.org/10.1073/pnas.2200477119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659396/
https://www.ncbi.nlm.nih.gov/pubmed/36322753
http://dx.doi.org/10.1073/pnas.2200477119

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