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IGF2BP2 promotes cancer progression by degrading the RNA transcript encoding a v-ATPase subunit
IGF2BP2 binds to a number of RNA transcripts and has been suggested to function as a tumor promoter, although little is known regarding the mechanisms that regulate its roles in RNA metabolism. Here we demonstrate that IGF2BP2 binds to the 3′ untranslated region of the transcript encoding ATP6V1A, a...
Autores principales: | Latifkar, Arash, Wang, Fangyu, Mullmann, James J., Panizza, Elena, Fernandez, Irma R., Ling, Lu, Miller, Andrew D., Fischbach, Claudia, Weiss, Robert S., Lin, Hening, Cerione, Richard A., Antonyak, Marc A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659396/ https://www.ncbi.nlm.nih.gov/pubmed/36322753 http://dx.doi.org/10.1073/pnas.2200477119 |
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