Ornithine decarboxylase supports ILC3 responses in infectious and autoimmune colitis through positive regulation of IL-22 transcription

Group 3 innate lymphoid cells (ILC3s) are RORγT(+) lymphocytes that are predominately enriched in mucosal tissues and produce IL-22 and IL-17A. They are the innate counterparts of Th17 cells. While Th17 lymphocytes utilize unique metabolic pathways in their differentiation program, it is unknown whe...

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Detalles Bibliográficos
Autores principales: Peng, Vincent, Cao, Siyan, Trsan, Tihana, Bando, Jennifer K., Avila-Pacheco, Julian, Cleveland, John L., Clish, Clary, Xavier, Ramnik J., Colonna, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659397/
https://www.ncbi.nlm.nih.gov/pubmed/36279426
http://dx.doi.org/10.1073/pnas.2214900119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659397/
https://www.ncbi.nlm.nih.gov/pubmed/36279426
http://dx.doi.org/10.1073/pnas.2214900119

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