An autologous humanized patient-derived xenograft (PDX) model for evaluation of nivolumab immunotherapy in renal cell cancer: a case report

BACKGROUND: There is an unmet need for developing faithful animal models for preclinical evaluation of immunotherapy. The current approach to generate preclinical models for immunotherapy evaluation has been to transplant CD34(+) cells from umbilical cord blood into immune-deficient mice followed by...

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Detalles Bibliográficos
Autores principales: Kang, Yubin, Armstrong, Andrew J., Hsu, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659479/
https://www.ncbi.nlm.nih.gov/pubmed/36393918
http://dx.doi.org/10.21037/sci-2022-029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659479/
https://www.ncbi.nlm.nih.gov/pubmed/36393918
http://dx.doi.org/10.21037/sci-2022-029

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