Cargando…

An autologous humanized patient-derived xenograft (PDX) model for evaluation of nivolumab immunotherapy in renal cell cancer: a case report

BACKGROUND: There is an unmet need for developing faithful animal models for preclinical evaluation of immunotherapy. The current approach to generate preclinical models for immunotherapy evaluation has been to transplant CD34(+) cells from umbilical cord blood into immune-deficient mice followed by...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kang, Yubin, Armstrong, Andrew J., Hsu, David S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659479/ https://www.ncbi.nlm.nih.gov/pubmed/36393918 http://dx.doi.org/10.21037/sci-2022-029

Ejemplares similares

Patient-derived xenograft (PDX) tumors increase growth rate with time
por: Pearson, Alexander T., et al.
Publicado: (2016)

Patient-derived xenograft (PDX) models, applications and challenges in cancer research
por: Abdolahi, Shahrokh, et al.
Publicado: (2022)

CombPDX: a unified statistical framework for evaluating drug synergism in patient-derived xenografts
por: Huang, Licai, et al.
Publicado: (2022)

PDX Finder: A portal for patient-derived tumor xenograft model discovery
por: Conte, Nathalie, et al.
Publicado: (2019)

Application of Highly Immunocompromised Mice for the Establishment of Patient-Derived Xenograft (PDX) Models
por: Okada, Seiji, et al.
Publicado: (2019)

Factors that influence response classifications in chemotherapy treated patient-derived xenografts (PDX)
por: Malcolm, Joan E., et al.
Publicado: (2019)

Patient-derived xenograft (PDX) models: characteristics and points to consider for the process of establishment
por: Fujii, Etsuko, et al.
Publicado: (2020)

Characterization of the large‐scale Japanese patient‐derived xenograft (J‐PDX) library
por: Yagishita, Shigehiro, et al.
Publicado: (2021)

A participant-derived xenograft model of HIV enables long-term evaluation of autologous immunotherapies
por: McCann, Chase D., et al.
Publicado: (2021)

Patient derived xenografts (PDX) predict an effective heparanase-based therapy for lung cancer
por: Katz, Amit, et al.
Publicado: (2018)

Capturing colorectal cancer inter‐tumor heterogeneity in patient‐derived xenograft (PDX) models
por: Prasetyanti, Pramudita R., et al.
Publicado: (2018)

Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment
por: Chiorazzi, Michael, et al.
Publicado: (2023)

P1224: PATIENT-DERIVED XENOGRAFT (PDX) IS A USEFUL TOOL FOR EVALUATING 5-AZACYTIDINE SENSITIVITY IN TFH LYMPHOMAS
por: Tari, Gamze, et al.
Publicado: (2023)

Establishment and characterization of immortalized human breast cancer cell lines from breast cancer patient-derived xenografts (PDX)
por: Zhuang, Yongxian, et al.
Publicado: (2021)

Mouse Models in Prostate Cancer Translational Research: From Xenograft to PDX
por: Rea, Domenica, et al.
Publicado: (2016)

Autologous humanized mouse models to study combination and single-agent immunotherapy for colorectal cancer patient-derived xenografts
por: Kanikarla Marie, Preeti, et al.
Publicado: (2022)

Development of a Patient-Derived Xenograft (PDX) of Breast Cancer Bone Metastasis in a Zebrafish Model
por: Mercatali, Laura, et al.
Publicado: (2016)

Changes in the Urinary Proteome in a Patient-Derived Xenograft (PDX) Nude Mouse Model of Colorectal Tumor
por: Liu, Yongtao, et al.
Publicado: (2019)

An Orthotopic Patient-Derived Xenograft (PDX) Model Allows the Analysis of Metastasis-Associated Features in Colorectal Cancer
por: De Angelis, Maria Laura, et al.
Publicado: (2022)

Establishment and Characterization of Humanized Mouse NPC-PDX Model for Testing Immunotherapy
por: Liu, Wai Nam, et al.
Publicado: (2020)

A systematic review of the validity of patient derived xenograft (PDX) models: the implications for translational research and personalised medicine
por: Collins, Anne T., et al.
Publicado: (2018)

Humanized Ovarian Cancer Patient-Derived Xenografts for Improved Preclinical Evaluation of Immunotherapies
por: Kleinmanns, Katrin, et al.
Publicado: (2022)

Impact of pemetrexed chemotherapy on the gut microbiota and intestinal inflammation of patient-lung-derived tumor xenograft (PDX) mouse models
por: Pensec, Cindy, et al.
Publicado: (2020)

Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine
por: Rivera, Maria, et al.
Publicado: (2020)

Statistical analysis of comparative tumor growth repeated measures experiments in the ovarian cancer patient derived xenograft (PDX) setting
por: Oberg, Ann L., et al.
Publicado: (2021)

Label-free separation of neuroblastoma patient-derived xenograft (PDX) cells from hematopoietic progenitor cell products by acoustophoresis
por: Olm, Franziska, et al.
Publicado: (2021)

Patient Derived Xenografts (PDX) Models as an Avatar to Assess Personalized Therapy Options in Uveal Melanoma: A Feasibility Study
por: Nemati, Fariba, et al.
Publicado: (2023)

Establishment and characterization of a cell line and patient-derived xenograft (PDX) from peritoneal metastasis of low-grade serous ovarian carcinoma
por: De Thaye, Elien, et al.
Publicado: (2020)

Studying cancer immunotherapy using patient-derived xenografts (PDXs) in humanized mice
por: Choi, Yunsik, et al.
Publicado: (2018)

Deep Learning Segmentation of Triple-Negative Breast Cancer (TNBC) Patient Derived Tumor Xenograft (PDX) and Sensitivity of Radiomic Pipeline to Tumor Probability Boundary
por: Dutta, Kaushik, et al.
Publicado: (2021)

Generation of Orthotopic Patient-Derived Xenografts in Humanized Mice for Evaluation of Emerging Targeted Therapies and Immunotherapy Combinations for Melanoma
por: Yan, Chi, et al.
Publicado: (2023)

Construction of a Humanized PBMC-PDX Model to Study the Efficacy of a Bacterial Marker in Lung Cancer Immunotherapy
por: Wu, Chengwei, et al.
Publicado: (2022)

PDX-derived organoids model in vivo drug response and secrete biomarkers
por: Huang, Ling, et al.
Publicado: (2020)

The Influence of Tissue Ischemia Time on RNA Integrity and Patient-Derived Xenografts (PDX) Engraftment Rate in a Non-Small Cell Lung Cancer (NSCLC) Biobank
por: Guerrera, Francesco, et al.
Publicado: (2016)

Onychopathy Induced by Nivolumab: A Targeted Immunotherapy
por: Zahoor, Fatima, et al.
Publicado: (2022)

Myocarditis and myasthenia gravis by combined nivolumab and ipilimumab immunotherapy for renal cell carcinoma: A case report of successful management
por: Yanase, Takahiro, et al.
Publicado: (2020)

Pyridoxal phosphate synthases PdxS/PdxT are required for Actinobacillus pleuropneumoniae viability, stress tolerance and virulence
por: Xie, Fang, et al.
Publicado: (2017)

Solution Structures and Dynamic Assembly of the 24-Meric Plasmodial Pdx1–Pdx2 Complex
por: Ullah, Najeeb, et al.
Publicado: (2020)

Generation of stable PDX derived cell lines using conditional reprogramming
por: Borodovsky, Alexandra, et al.
Publicado: (2017)

Development of humanized mouse with patient‐derived xenografts for cancer immunotherapy studies: A comprehensive review
por: Jin, Ke‐Tao, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_cojnc7jlb9mv1vcn2j0lbgm86m