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Paradoxical attenuation of neuroinflammatory response upon LPS challenge in miR-146b deficient mice

The miR-146 family consists of two microRNAs (miRNAs), miR-146a and miR-146b (miR-146a/b), both of which are known to suppress immune responses in a variety of conditions. Here, we studied how constitutive deficiency of miR-146b (Mir146b-/-) affects lipopolysaccharide (LPS)-induced neuroinflammation...

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Detalles Bibliográficos
Autores principales: Chithanathan, Keerthana, Jürgenson, Monika, Guha, Mithu, Yan, Ling, Žarkovskaja, Tamara, Pook, Martin, Magilnick, Nathaniel, Boldin, Mark P., Rebane, Ana, Tian, Li, Zharkovsky, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659615/
https://www.ncbi.nlm.nih.gov/pubmed/36389659
http://dx.doi.org/10.3389/fimmu.2022.996415