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Polygenic hazard score modified the relationship between hippocampal subfield atrophy and episodic memory in older adults

BACKGROUND: Understanding genetic influences on Alzheimer’s disease (AD) may improve early identification. Polygenic hazard score (PHS) is associated with the age of AD onset and cognitive decline. It interacts with other risk factors, but the nature of such combined effects remains poorly understoo...

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Detalles Bibliográficos
Autores principales: Xu, Jingjing, Guan, Xiaojun, Wen, Jiaqi, Zhang, Minming, Xu, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659745/
https://www.ncbi.nlm.nih.gov/pubmed/36389062
http://dx.doi.org/10.3389/fnagi.2022.943702