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Improving the ex vivo expansion of human tumor-reactive CD8 + T cells by targeting toll-like receptors

Toll-like receptors (TLRs) are important pattern recognition receptor(s) known to mediate the sensing of invading pathogens and subsequent immune responses. In this study, we investigate whether TLRs could be explored for the preparation of human CD8(+) T cell products used in adoptive cell therapy...

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Detalles Bibliográficos
Autores principales: Qiu, Chenli, Wang, Jing, Zhu, Lingyan, Cheng, Xiaobo, Xia, Bili, Jin, Yanling, Qin, Ran, Zhang, LinXia, Hu, Huiliang, Yan, Jia, Zhao, Chen, Zhang, Xiaoyan, Xu, Jianqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659750/
https://www.ncbi.nlm.nih.gov/pubmed/36394017
http://dx.doi.org/10.3389/fbioe.2022.1027619