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Changes in gap junction proteins Connexin30.2 and Connexin40 expression in the sinoatrial node of rats with dexmedetomidine-induced sinus bradycardia

BACKGROUND: Dexmedetomidine (Dex) is widely used, and its most common side effect is bradycardia. The complete mechanism through which Dex induces bradycardia has not been elucidated. This research investigates the expression of gap junction proteins Connexin30.2 (Cx30.2) and Connexin40 (Cx40) withi...

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Detalles Bibliográficos
Autores principales: Yin, Yong-Qiang, Zhong, Yi, Zhu, Yu, Tian, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659980/
https://www.ncbi.nlm.nih.gov/pubmed/35618083
http://dx.doi.org/10.1016/j.bjane.2022.05.004