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Progression of the tumor in a patient with a gastrointestinal stromal tumor with the PDGFRA exon 12 mutation who received multiple surgeries and multiple lines of tyrosine kinase inhibitor therapies: a case report

BACKGROUND: Targeted therapy with tyrosine kinase inhibitors (TKIs) benefits most patients with stromal tumors; however, the effects of TKIs in patients with rare cases of gastrointestinal stromal tumors (GISTs) with platelet-derived growth factor receptor alpha (PDGFRA) exon 12 mutations are unclea...

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Detalles Bibliográficos
Autores principales: An, Zhaojie, Tan, Ming, Xia, Yuxiang, Li, Yong, Fan, Liqiao, Zhao, Qun, Zhang, Zhidong, Tan, Bibo, Liu, Yu, Ma, Zhixue, Wang, Dong, Zhao, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9660055/
https://www.ncbi.nlm.nih.gov/pubmed/36388657
http://dx.doi.org/10.21037/jgo-22-791