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Intimate intertwining of the pathogenesis of hypoxia and systemic sclerosis: A transcriptome integration analysis

OBJECTIVES: Systemic sclerosis (SSc) is an autoimmune disease caused by various pathogenic factors, including hypoxia. Hypoxia stimulates the production of the extracellular matrix to promote fibrosis. However, the integrated function and the underlying mechanism of hypoxia in SSc are unclear. METHO...

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Detalles Bibliográficos
Autores principales: He, Xinglan, Shi, Yaqian, Zeng, Zhuotong, Tang, Bingsi, Xiao, Xuan, Yu, Jiangfan, Zou, Puyu, Liu, Jiani, Xiao, Yangfan, Luo, Yangyang, Xiao, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9660309/
https://www.ncbi.nlm.nih.gov/pubmed/36389675
http://dx.doi.org/10.3389/fimmu.2022.929289