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Single-cell RNA-sequencing uncovers compound kushen injection synergistically improves the efficacy of chemotherapy by modulating the tumor environment of breast cancer

BACKGROUND: Due to lack of enough specific targets and the immunosuppressive tumor microenvironment (TME) of triple-negative breast cancer (TNBC), TNBC patients often cannot benefit from a single treatment option. This study aims to explore the regulatory effects of Compound kushen injection (CKI) p...

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Detalles Bibliográficos
Autores principales: Liu, Xinkui, Bai, Meirong, Li, Huiying, Ye, Peizhi, Duan, Xiaoxia, Wu, Chao, Huang, Zhihong, Lu, Shan, Zhang, Jingyuan, Zhao, Zihan, Guo, Fengying, You, Rongli, Qin, Wenjie, Wang, Wei, Han, Aiqing, Shen, Liangliang, Wang, Yitao, Zhao, Zheng, Luo, Hua, Wu, Jiarui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9660330/
https://www.ncbi.nlm.nih.gov/pubmed/36389835
http://dx.doi.org/10.3389/fimmu.2022.965342