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Bumetanide attenuates sevoflurane‐induced neuroapoptosis in the developing dentate gyrus and impaired behavior in the contextual fear discrimination learning test

INTRODUCTION: Sevoflurane acts as a gamma‐aminobutyric acid subtype A receptor agonist and can induce widespread apoptosis of immature dentate granule cells in postnatal day 21 mice. The dentate granule cells of postnatal day 21 mice undergo a developmental stage when gamma‐aminobutyric acid (GABA)...

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Detalles Bibliográficos
Autores principales: Wei, Kai, Liu, Yiheng, Yang, Xiamin, Liu, Jin, Li, Yuan, Deng, Meng, Wang, Yingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9660414/
https://www.ncbi.nlm.nih.gov/pubmed/36184814
http://dx.doi.org/10.1002/brb3.2768