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Targeting microglial NLRP3 in the SNc region as a promising disease‐modifying therapy for Parkinson's disease
INTRODUCTION: Parkinson's disease (PD) is a neurodegenerative disorder characterized by progressive loss of dopaminergic (DA) neurons. Accumulating evidence has shown that activation of the NLR family pyrin domain‐containing 3 (NLRP3) inflammasome is an early and cardinal feature in PD progress...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9660492/ https://www.ncbi.nlm.nih.gov/pubmed/36199191 http://dx.doi.org/10.1002/brb3.2784 |