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Targeting microglial NLRP3 in the SNc region as a promising disease‐modifying therapy for Parkinson's disease

INTRODUCTION: Parkinson's disease (PD) is a neurodegenerative disorder characterized by progressive loss of dopaminergic (DA) neurons. Accumulating evidence has shown that activation of the NLR family pyrin domain‐containing 3 (NLRP3) inflammasome is an early and cardinal feature in PD progress...

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Detalles Bibliográficos
Autores principales: Qiao, Chen, Dang, Tao, Zhou, Yan, Zhou, Yuan‐Zhang, Zhao, Rong, Wang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9660492/
https://www.ncbi.nlm.nih.gov/pubmed/36199191
http://dx.doi.org/10.1002/brb3.2784