Cargando…
Targeting microglial NLRP3 in the SNc region as a promising disease‐modifying therapy for Parkinson's disease
INTRODUCTION: Parkinson's disease (PD) is a neurodegenerative disorder characterized by progressive loss of dopaminergic (DA) neurons. Accumulating evidence has shown that activation of the NLR family pyrin domain‐containing 3 (NLRP3) inflammasome is an early and cardinal feature in PD progress...
Autores principales: | Qiao, Chen, Dang, Tao, Zhou, Yan, Zhou, Yuan‐Zhang, Zhao, Rong, Wang, Min |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9660492/ https://www.ncbi.nlm.nih.gov/pubmed/36199191 http://dx.doi.org/10.1002/brb3.2784 |
Ejemplares similares
-
Parkin regulates microglial NLRP3 and represses neurodegeneration in Parkinson's disease
por: Yan, Yi‐Qun, et al.
Publicado: (2023) -
Targeting Microglial α-Synuclein/TLRs/NF-kappaB/NLRP3 Inflammasome Axis in Parkinson’s Disease
por: Li, Yunna, et al.
Publicado: (2021) -
Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer’s disease
por: Zhou, Xiao-Gang, et al.
Publicado: (2022) -
Dopamine signaling modulates microglial NLRP3 inflammasome activation: implications for Parkinson’s disease
por: Pike, Adrianne F., et al.
Publicado: (2022) -
sncRNA changes induced by tension in hypertrophic scar: sncRNAs in hypertrophic scar
por: Yin, Chuang, et al.
Publicado: (2022)