Family History of Prostate and Breast Cancer Integrated with a Polygenic Risk Score Identifies Men at Highest Risk of Dying from Prostate Cancer before Age 75 Years

PURPOSE: Family history of prostate cancer is one of the few universally accepted risk factors for prostate cancer. How much an assessment of inherited polygenic risk for prostate cancer adds to lifetime risk stratification beyond family history is unknown. EXPERIMENTAL DESIGN: We followed 10,120 me...

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Detalles Bibliográficos
Autores principales: Plym, Anna, Zhang, Yiwen, Stopsack, Konrad H., Jee, Yon Ho, Wiklund, Fredrik, Kibel, Adam S., Kraft, Peter, Giovannucci, Edward, Penney, Kathryn L., Mucci, Lorelei A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Precision Medicine and Imaging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9660541/
https://www.ncbi.nlm.nih.gov/pubmed/36103261
http://dx.doi.org/10.1158/1078-0432.CCR-22-1723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9660541/
https://www.ncbi.nlm.nih.gov/pubmed/36103261
http://dx.doi.org/10.1158/1078-0432.CCR-22-1723

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