Evaluation of a connexin-based peptide for the treatment of age-related macular degeneration

A critical target in age-related macular degeneration (AMD) is the retinal pigment epithelium (RPE), which forms the outer blood-retina barrier (BRB). RPE-barrier dysfunction might result from the disruption of intercellular tight junctions (TJs). A Connexin43 (Cx43)-based peptide, aCT1, has been sh...

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Detalles Bibliográficos
Autores principales: Obert, Elisabeth, Grek, Christina, Ghatnekar, Gautam, Rohrer, Bärbel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9660603/
https://www.ncbi.nlm.nih.gov/pubmed/36387470
http://dx.doi.org/10.1016/j.heliyon.2022.e11359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9660603/
https://www.ncbi.nlm.nih.gov/pubmed/36387470
http://dx.doi.org/10.1016/j.heliyon.2022.e11359

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