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Evaluation of a connexin-based peptide for the treatment of age-related macular degeneration
A critical target in age-related macular degeneration (AMD) is the retinal pigment epithelium (RPE), which forms the outer blood-retina barrier (BRB). RPE-barrier dysfunction might result from the disruption of intercellular tight junctions (TJs). A Connexin43 (Cx43)-based peptide, aCT1, has been sh...
Autores principales: | Obert, Elisabeth, Grek, Christina, Ghatnekar, Gautam, Rohrer, Bärbel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9660603/ https://www.ncbi.nlm.nih.gov/pubmed/36387470 http://dx.doi.org/10.1016/j.heliyon.2022.e11359 |
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